Description

n-Methyl-1,2,3,4-Tetrahydroisoquinoline Hydrochloride is a versatile organic salt and a key synthetic intermediate in advanced chemical synthesis. Its value lies in its role as a crucial building block for constructing complex nitrogen-containing heterocycles, which are foundational to numerous high-value applications. This compound is essential for research and development laboratories, pharmaceutical manufacturers, and fine chemical producers focused on creating novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of various alkaloids and potential therapeutic agents targeting the central nervous system.
• Agrochemical Synthesis: Used as a building block for developing novel pesticides and herbicides with specific biological activity.
• Organic Synthesis & Research: Serves as a versatile reagent for constructing complex tetrahydroisoquinoline scaffolds in academic and industrial R&D.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, dyes, and advanced materials requiring specific nitrogen heterocycle structures.
• Ligand & Catalyst Development: Acts as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.

Basic Information

Product Name	n-Methyl-1,2,3,4-Tetrahydroisoquinoline Hydrochloride
CAS No.	53112-33-7
Molecular Formula	C₁₀H₁₄ClN
Molecular Weight	183.68 g/mol
Synonyms	1-Methyl-1,2,3,4-tetrahydroisoquinoline hydrochloride; N-Methyl-THIQ hydrochloride; N-Methyl-1,2,3,4-tetrahydroisoquinolinium chloride; 2-Methyl-1,2,3,4-tetrahydroisoquinoline hydrochloride; N-Methyl-3,4-dihydro-1(2H)-isoquinoline hydrochloride; N-Methyl-1,2,3,4-tetrahydroisoquinoline HCl; N-Methyl-THIQ HCl
EINECS	Contact for details

Quality Control

Our n-Methyl-1,2,3,4-Tetrahydroisoquinoline Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets high-grade specifications for research and industrial use. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.