Description

2-Acetylamino-1-O,3-O,4-O,6-o-Tetrakis(Trimethylsilyl)-2-Deoxy-α-D-Mannopyranose is a key protected carbohydrate derivative, specifically a per-silylated N-acetyl mannosamine, essential for advanced synthetic organic chemistry. Its value lies in providing a stable, reactive intermediate with multiple silyl ether protecting groups, enabling precise, multi-step glycosylation and oligosaccharide assembly. This compound is critically needed by research chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries for the synthesis of complex glycoconjugates, glycomimetics, and novel therapeutic agents.

Application

• Glycosylation Building Block: A crucial protected intermediate for the stereoselective synthesis of complex oligosaccharides and glycans.
• Pharmaceutical Intermediate: Used in the research and development of glycan-based drugs, including antiviral agents, cancer vaccines, and anti-inflammatory therapeutics.
• Glycoconjugate Synthesis: Serves as a key precursor for creating glycoproteins, glycolipids, and other biologically active conjugates.
• Chemical Biology Probes: Enables the development of labeled or modified sugars for studying carbohydrate-protein interactions and metabolic pathways.
• Process Chemistry: Employed in scale-up and optimization of synthetic routes for high-value carbohydrate targets under controlled conditions.
• Academic & Institutional Research: A vital reagent for fundamental studies in synthetic carbohydrate chemistry and glycoscience.

Basic Information

Product Name	2-Acetylamino-1-O,3-O,4-O,6-o-Tetrakis(Trimethylsilyl)-2-Deoxy-α-D-Mannopyranose
CAS No.	53110-70-6
Molecular Formula	C22H51NO6Si4
Molecular Weight	537.99 g/mol
Synonyms	1,3,4,6-Tetra-O-trimethylsilyl-2-acetamido-2-deoxy-α-D-mannopyranose; N-Acetyl-1,3,4,6-tetra-O-trimethylsilyl-α-D-mannosamine; 2-Acetamido-1,3,4,6-tetra-O-(trimethylsilyl)-2-deoxy-α-D-mannopyranose; Per-O-trimethylsilylated N-Acetylmannosamine; TMS-protected N-Acetyl-α-D-mannosamine; α-D-ManNAc(1,3,4,6-OTMS)4; Protected D-Mannosamine Derivative
EINECS	Contact for details

Quality Control

Our 2-Acetylamino-1-O,3-O,4-O,6-o-Tetrakis(Trimethylsilyl)-2-Deoxy-α-D-Mannopyranose is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is characterized by advanced analytical techniques including NMR, HPLC, and mass spectrometry. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (argon or nitrogen) after opening to prevent decomposition. Keep the container tightly sealed in a desiccator when not in use.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.