Description

[1-[(Trimethylsilyl)Amino]Butyl]Phosphonic Acid Bis(Trimethylsilyl) Ester is a specialized organosilicon-protected phosphonic acid derivative, serving as a key synthetic intermediate and protecting group reagent. Its primary value lies in enabling advanced organic synthesis, particularly in the preparation of complex molecules where selective deprotection is required. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity, moisture-sensitive building blocks for sophisticated chemical processes.

Application

• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing phosphonate or aminophosphonate moieties.
• Agrochemical Synthesis: Serves as a protected precursor for creating novel herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Employed in the preparation of specialized phosphonate-based ligands for metal catalysis and coordination chemistry.
• Peptide Mimetics and Prodrugs: Acts as a key building block for phosphonate-containing peptide analogs and prodrug strategies.
• Surface Modification Agent: Utilized for the functionalization of metal oxides and other surfaces in materials science applications.
• Chemical Biology Probes: Incorporated into molecules designed to study enzyme mechanisms, particularly those involving phosphate transfer.

Basic Information

Product Name	[1-[(Trimethylsilyl)Amino]Butyl]Phosphonic Acid Bis(Trimethylsilyl) Ester
CAS No.	53044-39-6
Molecular Formula	C13H34NO3PSi3
Molecular Weight	367.65 g/mol
Synonyms	1-[(Trimethylsilyl)Amino]Butylphosphonic Acid Bis(Trimethylsilyl) Ester; Butyl[1-[(trimethylsilyl)amino]]phosphonic Acid Bis(trimethylsilyl) Ester; Phosphonic Acid, P-[1-[(trimethylsilyl)amino]butyl]-, Bis(trimethylsilyl) Ester; (1-((Trimethylsilyl)amino)butyl)phosphonic Acid Bis(trimethylsilyl) Ester; TMS-Protected Aminobutylphosphonate; N-(Trimethylsilyl)-4-aminobutylphosphonic Acid Bis(TMS) Ester
EINECS	Contact for details

Quality Control

Our production of [1-[(Trimethylsilyl)Amino]Butyl]Phosphonic Acid Bis(Trimethylsilyl) Ester adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. All materials are characterized by modern analytical techniques including NMR, HPLC, and GC. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.