Description

Methylenebisphosphonic Acid Tetrakis(Trimethylsilyl) Ester is a key organosilicon-protected derivative of methylenebisphosphonic acid, widely used as a versatile synthetic intermediate and protecting group reagent. This compound is particularly valued for its role in modifying the solubility and reactivity of phosphonate groups in complex organic and organometallic synthesis. It is an essential material for researchers and manufacturers in the fields of pharmaceutical development, advanced material science, and specialty chemical production, where precise control over phosphonate chemistry is required.

Application

• Pharmaceutical Intermediate: Serves as a protected precursor in the synthesis of bisphosphonate drugs for treating bone disorders.
• Ligand Synthesis: Used to prepare complexing agents and chelating ligands for metal catalysis and separation processes.
• Material Science: Acts as a monomer or surface-modifying agent in the development of functional polymers and hybrid inorganic-organic materials.
• Chemical Research: Employed as a key reagent in organic synthesis for the selective introduction and deprotection of phosphonate functionalities.
• Agrochemical Development: Utilized in the research and synthesis of novel plant growth regulators and herbicides containing phosphonate groups.
• Flame Retardant Formulation: Investigated as a potential component or intermediate in the production of phosphorus-based flame retardant additives.

Basic Information

Product Name	Methylenebisphosphonic Acid Tetrakis(Trimethylsilyl) Ester
CAS No.	53044-26-1
Molecular Formula	C13H38O6P2Si4
Molecular Weight	452.78 g/mol
Synonyms	Methylenebis(phosphonic acid) tetrakis(trimethylsilyl) ester; Tetrakis(trimethylsilyl) methylenediphosphonate; P,P'-(Methylenebis-P,P'-bis(trimethylsilyl) phosphonate); MBPTTMS; Methylenediphosphonic Acid Tetrakis(trimethylsilyl) Ester; Bis(trimethylsilyl) methylenebis(phosphonate) bis(trimethylsilyl) ester; 1,1-Bis[bis(trimethylsilyloxy)phosphoryl]methane
EINECS	Contact for details

Quality Control

Our production of Methylenebisphosphonic Acid Tetrakis(Trimethylsilyl) Ester adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is characterized using advanced analytical techniques, including NMR, HPLC, and GC, to verify identity and quantify impurities. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and specific test results is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. This product is hygroscopic (moisture-sensitive) and should be stored under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place. Recommended storage temperature is 2-8°C for long-term stability. Keep away from strong acids and organic solvents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
1H NMR	Conforms to structure
31P NMR	Conforms to structure
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.