Description

1-Aminoisoquinoline-4-Carbonitrile is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound matters for its role as a key precursor in the development of complex molecules with significant biological activity. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries, as well as by fine chemical manufacturers specializing in custom synthesis.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of kinase inhibitors and other small-molecule drug candidates targeting various therapeutic areas.
• Agrochemical Research: Used in the development of novel herbicides and pesticides, leveraging its heterocyclic core for bioactivity.
• Material Science: Serves as a building block for creating organic semiconductors, ligands for metal-organic frameworks (MOFs), and specialty polymers.
• Dye and Pigment Synthesis: Employed in the production of advanced colorants and fluorescent markers due to its conjugated isoquinoline structure.
• Academic & Contract Research: A valuable reagent for methodological development and exploratory chemistry in university and CRO laboratories.

Basic Information

Product Name	1-Aminoisoquinoline-4-Carbonitrile
CAS No.	53000-57-0
Molecular Formula	C10H7N3
Molecular Weight	169.18 g/mol
Synonyms	4-Cyano-1-aminoisoquinoline; 1-Isoquinolinamine, 4-cyano-; 1-Amino-4-cyanoisoquinoline; Isoquinoline-1-amine, 4-cyano-; 1-Aminoisoquinoline-4-carbonitrile; 4-CN-1-NH2-Isoquinoline; 1-Amino-4-cyano-isoquinoline
EINECS	Contact for details

Quality Control

Our 1-Aminoisoquinoline-4-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing all specifications are available upon request, supporting compliance with research and cGMP guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic (moisture-sensitive) nature, store under an inert atmosphere such as nitrogen or argon in a cool, dry place. Recommended long-term storage temperature is 2-8°C. Allow the sealed container to equilibrate to room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.