Description

5-(2-Methylpropyl)-5-(2-Propenyl)-1,3-Bis(Trimethylsilyl)-2,4,6(1H,3H,5H)-Pyrimidinetrione is a specialized organosilicon-protected pyrimidinetrione derivative, offering a unique combination of reactivity and stability for advanced synthetic chemistry. This compound is valued for its role as a key synthetic intermediate or protecting group reagent in the development of complex organic molecules. It is primarily needed by research and development laboratories, pharmaceutical manufacturers, and fine chemical producers engaged in the synthesis of novel active pharmaceutical ingredients (APIs), agrochemicals, and high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the multi-step synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and plant growth regulators.
• Fine Chemical Production: Acts as a key reagent for the manufacture of high-purity, specialty chemicals used in electronics, materials science, and catalysis.
• Academic & Industrial R&D: Employed in research laboratories for methodological development and exploring new chemical entities.
• Protecting Group Chemistry: The bis(trimethylsilyl) groups can be utilized to protect reactive sites during complex synthetic sequences.
• Process Chemistry Development: Investigated for use in scalable manufacturing processes for niche chemical products.

Basic Information

Product Name	5-(2-Methylpropyl)-5-(2-Propenyl)-1,3-Bis(Trimethylsilyl)-2,4,6(1H,3H,5H)-Pyrimidinetrione
CAS No.	52937-70-9
Molecular Formula	C17H32N2O3Si2
Molecular Weight	368.62 g/mol
Synonyms	1,3-Bis(trimethylsilyl)-5-(2-methylpropyl)-5-(2-propenyl)-2,4,6-pyrimidinetrione; 5-Isobutyl-5-allyl-1,3-bis(trimethylsilyl)barbituric acid; 5-Allyl-5-isobutyl-1,3-bis(trimethylsilyl)barbituric acid; Allylisobutylbarbituric acid bis(trimethylsilyl) derivative; TMS-protected allylisobutylbarbiturate; Bis(trimethylsilyl) allylisobutylbarbiturate; Silylated barbiturate derivative
EINECS	Contact for details

Quality Control

Our 5-(2-Methylpropyl)-5-(2-Propenyl)-1,3-Bis(Trimethylsilyl)-2,4,6(1H,3H,5H)-Pyrimidinetrione is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications such as assay (by HPLC), identity (by IR/NMR), and impurity profiles are available upon request. We adhere to cGMP standards where applicable to support our clients in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.