Description

5-Ethyl-5-(1-Methylpropyl)-1,3-Bis(Trimethylsilyl)-2,4,6(1H,3H,5H)-Pyrimidinetrione is a specialized organosilicon-protected derivative of a barbiturate-type structure, offering a valuable synthon for advanced organic synthesis. This compound matters for its role as a key protected intermediate, enabling precise chemical modifications in sensitive environments where standard functional groups are incompatible. Pharmaceutical R&D and fine chemical manufacturers need it for developing novel active ingredients and complex molecular architectures, particularly in central nervous system (CNS) drug discovery and specialty material science.

Application

• Pharmaceutical Intermediate: Serves as a protected precursor in the synthesis of novel barbiturate analogs and other heterocyclic compounds with potential therapeutic activity.
• Advanced Organic Synthesis: Used as a building block in multi-step syntheses requiring the selective manipulation of the pyrimidinetrione core under mild conditions.
• Chemical Research & Development: Employed in academic and industrial R&D labs for exploring new reaction pathways and developing proprietary synthetic methodologies.
• Material Science Precursor: Potential use in the development of silicon-incorporated organic frameworks or specialty polymers with unique properties.
• Reference Standard: Can be utilized as an analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	5-Ethyl-5-(1-Methylpropyl)-1,3-Bis(Trimethylsilyl)-2,4,6(1H,3H,5H)-Pyrimidinetrione
CAS No.	52937-66-3
Molecular Formula	C₁₇H₃₄N₂O₃Si₂
Molecular Weight	370.63 g/mol
Synonyms	1,3-Bis(trimethylsilyl)-5-ethyl-5-(1-methylpropyl)barbituric acid; 5-Ethyl-5-(1-methylpropyl)-1,3-bis(trimethylsilyl)barbituric acid; 5-Ethyl-5-sec-butyl-1,3-bis(trimethylsilyl)barbituric acid; TMS-protected barbiturate derivative; 1,3-Bis-O-trimethylsilyl-5-ethyl-5-(1-methylpropyl)-2,4,6-pyrimidinetrione
EINECS	Contact for details

Quality Control

Our 5-Ethyl-5-(1-Methylpropyl)-1,3-Bis(Trimethylsilyl)-2,4,6(1H,3H,5H)-Pyrimidinetrione is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatographic purity assessment and structural confirmation, to ensure it meets high-purity standards suitable for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.