Description

4-Iodobenzene-1-Thiol is a versatile organosulfur building block characterized by its reactive thiol (-SH) and iodine substituents on an aromatic ring. This compound matters for its dual functionality, enabling it to act as a key intermediate in cross-coupling reactions and as a ligand precursor in material science. It is primarily needed by researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for synthesizing complex molecules and functional polymers.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing aryl sulfide or disulfide linkages.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides where the iodine and thiol groups facilitate structural diversification.
• Material Science & Polymer Chemistry: Acts as a monomer or chain-transfer agent in the production of specialty polymers and as a surface modifier for nanoparticles and quantum dots.
• Ligand Synthesis for Catalysis: Employed in the preparation of sulfur-containing ligands for transition metal catalysts used in organic synthesis.
• Cross-Coupling Reactions: Utilized in palladium-catalyzed reactions (e.g., Suzuki, Sonogashira) where the iodine acts as a leaving group, and the thiol can be further functionalized.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D for exploring new synthetic methodologies and creating molecular libraries.

Basic Information

Product Name	4-Iodobenzene-1-Thiol
CAS No.	52928-01-5
Molecular Formula	C6H5IS
Molecular Weight	236.07 g/mol
Synonyms	4-Iodobenzenethiol; p-Iodobenzenethiol; 4-Iodophenyl mercaptan; 1-Iodo-4-mercaptobenzene; 4-Iodothiophenol; p-Iodothiophenol; (4-Iodophenyl)thiol; Benzenethiol, 4-iodo-
EINECS	Contact for details

Quality Control

Our 4-Iodobenzene-1-Thiol is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available upon request to support your quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to minimize oxidation and degradation. Keep the container in a cool, dry, and well-ventilated place away from incompatible materials.

Specification

Item	Specification
Appearance	White to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.