Description

1-Hydroxy-3-Oxo-2,3,5,6,7,8-Hexahydroisoquinoline-4-Carbonitrile is a versatile heterocyclic building block and key synthetic intermediate prized for its unique fused bicyclic structure. This compound matters for its role in constructing complex molecular architectures, particularly in advanced pharmaceutical research and fine chemical synthesis. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, cardiovascular diseases, and anti-inflammatory agents.
• Agrochemical Synthesis: Serves as a key scaffold for developing new herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Organic Synthesis Building Block: Utilized in complex multi-step organic syntheses to construct fused nitrogen-containing heterocycles, which are prevalent in many bioactive molecules.
• Material Science Research: Investigated as a monomer or precursor for creating specialty polymers and advanced organic materials with specific electronic or photonic properties.
• Academic & Contract Research: Employed in university and CRO (Contract Research Organization) laboratories for methodological development and exploring new chemical spaces.

Basic Information

Product Name	1-Hydroxy-3-Oxo-2,3,5,6,7,8-Hexahydroisoquinoline-4-Carbonitrile
CAS No.	52903-71-6
Molecular Formula	C10H10N2O2
Molecular Weight	190.20 g/mol
Synonyms	4-Cyano-1-hydroxy-3-oxo-2,3,5,6,7,8-hexahydroisoquinoline; 1-Hydroxy-4-cyano-3-oxo-2,3,5,6,7,8-hexahydroisoquinoline; 3-Oxo-1-hydroxy-2,3,5,6,7,8-hexahydroisoquinoline-4-carbonitrile; 4-Cyano-1-hydroxy-3-oxo-1,2,5,6,7,8-hexahydroisoquinoline; 1-Hydroxy-3-oxo-1,2,5,6,7,8-hexahydroisoquinoline-4-carbonitrile; 2,3,5,6,7,8-Hexahydro-1-hydroxy-3-oxo-4-isoquinolinecarbonitrile
EINECS	Contact for details

Quality Control

Our 1-Hydroxy-3-Oxo-2,3,5,6,7,8-Hexahydroisoquinoline-4-Carbonitrile is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.