Description

(+)-Columbianetin CAS NO 52842-47-4 is a naturally occurring dihydrofurocoumarin derivative, a key chiral building block and reference standard in advanced organic synthesis. Its defined stereochemistry and unique fused ring structure make it a valuable intermediate for developing novel pharmaceutical and agrochemical compounds. This high-purity material is essential for researchers and manufacturers in the pharmaceutical, nutraceutical, and fine chemical industries focused on bioactive molecule development.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral precursor for the synthesis of potential drug candidates, particularly in oncology and anti-inflammatory research.
• Biochemical Research: Used as a reference standard and probe in pharmacological studies to investigate biological pathways and enzyme interactions.
• Natural Product Synthesis: A key starting material for the total or semi-synthesis of complex natural products and their analogs for structure-activity relationship (SAR) studies.
• Agrochemical Development: Employed in R&D for creating new plant growth regulators or bioactive agents with specific modes of action.
• Analytical Standard: Provides a high-purity benchmark for quality control and method validation in analytical laboratories (HPLC, LC-MS).

Basic Information

Product Name	(+)-Columbianetin
CAS No.	52842-47-4
Molecular Formula	C14H14O4
Molecular Weight	246.26 g/mol
Synonyms	(+)-Columbianetin; (3'R)-Columbianetin; (R)-Columbianetin; 2,3-Dihydro-7-hydroxy-2-[(1R)-1-hydroxy-1-methylethyl]-2H-furo[3,2-g][1]benzopyran-2-one; 7-Hydroxy-2,3-dihydro-2-(1-hydroxy-1-methylethyl)-furo[3,2-g]chromen-2-one; Columbianetin (enantiomer); Furo[3,2-g]chromen-2-one derivative
EINECS	Contact for details

Quality Control

Our (+)-Columbianetin is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the stringent requirements for research and development applications. A Certificate of Analysis (COA) detailing purity, identity, and chiral excess is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.