Description

Methyl 7-Deoxycholate-D5 is a deuterium-labeled derivative of the bile acid methyl deoxycholate, specifically designed for use as an internal standard in quantitative mass spectrometry. This compound is crucial for ensuring analytical accuracy and reproducibility in complex biological matrices. It is primarily utilized by researchers and quality control laboratories in the pharmaceutical, biotechnology, and diagnostic sectors for precise metabolic and pharmacokinetic studies.

Application

• Internal Standard for LC-MS/MS quantification of bile acids and related metabolites.
• Biomarker research and validation in studies of liver function and gastrointestinal diseases.
• Stable isotope dilution analysis in clinical diagnostics and metabolomics.
• Pharmacokinetic and drug metabolism studies in pharmaceutical R&D.
• Method development and validation for regulatory compliance in bioanalytical laboratories.
• Quality control of reference materials and assay kits in the diagnostics industry.

Basic Information

Product Name	Methyl 7-Deoxycholate-D5
CAS No.	52840-15-0
Molecular Formula	C25H37D5O4
Molecular Weight	407.60 g/mol (approx.)
Synonyms	7-Deoxycholic Acid Methyl Ester-d5; Methyl 7-Deoxycholate-d5; Methyl 3α,12α-Dihydroxy-5β-cholan-24-oate-d5; 3α,12α-Dihydroxy-5β-cholan-24-oic Acid Methyl Ester-d5; Deuterated Methyl Deoxycholate; Methyl Deoxycholate-d5; Cholan-24-oic Acid, 3,12-dihydroxy-, Methyl Ester-d5 (3α,5β,12α); Internal Standard for Bile Acid Analysis-d5
EINECS	Contact for details

Quality Control

Our Methyl 7-Deoxycholate-D5 is manufactured under strict quality systems to ensure high chemical purity and isotopic enrichment suitable for sensitive analytical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing purity, isotopic purity (D-enrichment), and identity confirmation. We adhere to relevant industry guidelines for reference standards and can provide material for method validation under GLP conditions.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation. The product is sensitive to light and should be handled under appropriate laboratory conditions.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR / NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-enrichment)	≥ 98 atom % D
Chemical Purity (by HPLC)	≥ 95.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.