Description

n-Methylpethidine is a synthetic organic compound belonging to the piperidine class, identified by CAS NO 52760-99-3. This chemical serves as a critical intermediate in advanced pharmaceutical synthesis, particularly in the development of specialized active pharmaceutical ingredients (APIs). It is essential for research and development laboratories, fine chemical manufacturers, and pharmaceutical companies engaged in the synthesis of complex therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex active pharmaceutical ingredients (APIs) and novel drug candidates.
• Research & Development: Used in medicinal chemistry and process development for creating new therapeutic compounds and optimizing synthetic pathways.
• Fine Chemical Synthesis: Employed as a specialized reagent in multi-step organic synthesis for producing high-value, complex molecules.
• Analytical Reference Standard: Serves as a certified reference material (CRM) for quality control, method development, and regulatory testing in analytical laboratories.

Basic Information

Product Name	n-Methylpethidine
CAS No.	52760-99-3
Molecular Formula	C16H23NO2
Molecular Weight	261.36 g/mol
Synonyms	1-Methyl-4-phenylpiperidine-4-carboxylic acid ethyl ester; Ethyl 1-methyl-4-phenylisonipecotate; Pethidine intermediate; Meperidine intermediate; Isonipecotic acid ethyl ester, 1-methyl-4-phenyl-; Demerol intermediate; 4-Carbethoxy-1-methyl-4-phenylpiperidine
EINECS	Contact for details

Quality Control

Our n-Methylpethidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation via IR and NMR spectroscopy, and residual solvent analysis to ensure it meets stringent specifications for pharmaceutical intermediate use. Certificates of Analysis (COA) documenting all test results are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.