Description

[S,(+)]-2,3-Dihydro-4-Hydroxy-7-Hydroxymethyl-2-(1-Hydroxy-1-Methylethyl)-5H-Furo[3,2-G][1]Benzopyran-5-One is a high-purity, optically active benzopyran derivative of significant interest in advanced organic synthesis. This compound matters as a sophisticated chiral building block and a key intermediate for the development of novel pharmaceutical agents and bioactive molecules. It is primarily needed by research and development teams in the pharmaceutical, agrochemical, and fine chemical industries for creating enantiomerically pure target compounds.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral precursor in the synthesis of potential drug candidates, particularly in therapeutic areas requiring high stereochemical purity.
• Asymmetric Synthesis: Utilized as a building block in catalytic and stoichiometric asymmetric reactions to construct complex molecular architectures.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and the development of new chemical entities (NCEs) with biological activity.
• Reference Standard: Used as an analytical standard for method development and quality control in laboratories producing or researching related compounds.
• Fine Chemical Synthesis: Acts as a starting material or intermediate for the production of specialty chemicals, flavors, and fragrances requiring specific stereochemistry.
• Agrochemical Development: Investigated as an intermediate for creating novel, enantiopure pesticides or plant growth regulators.

Basic Information

Product Name	[S,(+)]-2,3-Dihydro-4-Hydroxy-7-Hydroxymethyl-2-(1-Hydroxy-1-Methylethyl)-5H-Furo[3,2-G][1]Benzopyran-5-One
CAS No.	52589-21-6
Molecular Formula	C15H16O6
Molecular Weight	292.28 g/mol
Synonyms	(S)-5,6,7,8-Tetrahydro-2,8-dimethyl-5-oxo-4H,8H-pyrano[3,2-g]chromene-4,10-diol; (S)-Khellactone; (S)-(+)-Khellactone; (S)-4,9-Dihydroxy-3,3-dimethyl-10H-pyrano[2,3-f]chromen-10-one; 4,9-Dihydroxy-3,3-dimethyl-10H-pyrano[2,3-f]chromen-10-one (S-enantiomer); (+)-Khellactone; L-Khellactone; Contact for additional synonyms.
EINECS	Contact for details.

Quality Control

Our [S,(+)]-2,3-Dihydro-4-Hydroxy-7-Hydroxymethyl-2-(1-Hydroxy-1-Methylethyl)-5H-Furo[3,2-G][1]Benzopyran-5-One is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing identity, purity, and chiral excess are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent product degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.