Description

3-Amino-5-Nitrothieno[2,3-B]Pyridine-2-Carboxylic Acid Ethyl Ester is a high-purity, heterocyclic organic compound that serves as a critical advanced pharmaceutical intermediate and building block in synthetic chemistry. Its unique fused-ring structure containing amino and nitro functional groups makes it a versatile precursor for the development of novel active pharmaceutical ingredients (APIs). This compound is primarily sought by research institutions and pharmaceutical manufacturers engaged in the synthesis of complex molecules for therapeutic applications.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in research for central nervous system (CNS) and anti-infective agents.
• Organic Synthesis Research: Used in academic and industrial R&D for constructing complex heterocyclic frameworks due to its reactive amino and nitro groups.
• Agrochemical Development: Serves as a precursor in the research and synthesis of new-generation pesticides and herbicides.
• Material Science: Investigated as a monomer or precursor for specialty polymers and organic electronic materials.
• Dye and Pigment Synthesis: Utilized in the development of specialized colorants and functional dyes.

Basic Information

Product Name	3-Amino-5-Nitrothieno[2,3-B]Pyridine-2-Carboxylic Acid Ethyl Ester
CAS No.	52505-43-8
Molecular Formula	C10H9N3O4S
Molecular Weight	267.26 g/mol
Synonyms	Ethyl 3-Amino-5-nitrothieno[2,3-b]pyridine-2-carboxylate; 3-Amino-5-nitrothieno[2,3-b]pyridine-2-carboxylic acid ethyl ester; Thieno[2,3-b]pyridine-2-carboxylic acid, 3-amino-5-nitro-, ethyl ester; 52505-43-8; Ethyl 3-amino-5-nitro-4H-thieno[2,3-b]pyridine-2-carboxylate
EINECS	Contact for details

Quality Control

Our production of 3-Amino-5-Nitrothieno[2,3-B]Pyridine-2-Carboxylic Acid Ethyl Ester adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic identification (IR, NMR). A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption, which may affect stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.