Description

D-Tryptophanol is a chiral amino alcohol derivative of the essential amino acid tryptophan, serving as a critical chiral building block and intermediate in advanced organic synthesis. Its value lies in providing a stereochemically defined scaffold for constructing complex molecules, particularly in pharmaceutical research and development. This compound is essential for researchers and manufacturers in the pharmaceutical, biochemical, and fine chemical industries who require high-purity, optically active intermediates.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), especially those targeting neurological and metabolic pathways.
• Peptidomimetics Research: Used in the design and construction of peptide analogs and mimetics due to its indole side chain and alcohol functionality.
• Asymmetric Catalysis: Employed as a precursor for chiral ligands or catalysts in enantioselective synthesis.
• Bioconjugation & Probe Development: Useful for modifying biomolecules or creating fluorescent probes and diagnostic agents.
• Natural Product Synthesis: A building block for the total synthesis of complex natural products containing tryptophan-derived structures.
• Biochemical Research: Serves as a standard or reagent in enzymatic studies and metabolic pathway analysis.

Basic Information

Product Name	D-Tryptophanol
CAS No.	52485-52-6
Molecular Formula	C11H14N2O
Molecular Weight	190.24 g/mol
Synonyms	(R)-2-Amino-3-(1H-indol-3-yl)propan-1-ol; D-2-Amino-3-(3-indolyl)-1-propanol; (R)-Tryptophanol; (R)-β-(3-Indolyl)-α-aminopropanol; D-β-Indol-3-yl-α-aminopropanol; (R)-1-Amino-2-(1H-indol-3-yl)ethanol; D-Tryptophanol; (R)-Tryptophanol
EINECS	Contact for details

Quality Control

Our D-Tryptophanol is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and enantiomeric excess meet stringent specifications. Certificates of Analysis (COA) detailing purity (typically by HPLC), chiral purity, and residual solvent levels are provided and available upon request. We support compliance with cGMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee (D-isomer)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.