Description

Debromoaplysiatoxin is a potent bioactive polyketide compound derived from marine cyanobacteria. This molecule serves as a valuable biochemical tool for research due to its specific biological activity as a potent activator of protein kinase C (PKC). It is primarily utilized by researchers in the pharmaceutical, biotechnology, and life sciences sectors for studying signal transduction pathways, cancer biology, and as a reference standard in analytical chemistry.

Application

• Biochemical Research: As a potent and specific activator of protein kinase C (PKC) isoforms for studying intracellular signaling cascades.
• Pharmacological Studies: Used in vitro and in vivo research models to investigate the role of PKC in diseases such as cancer, inflammation, and neurological disorders.
• Reference Standard: High-purity grade serves as a critical analytical standard for method development, validation, and quality control in pharmaceutical R&D and contract testing laboratories.
• Toxicology Research: Investigation of cyanobacterial toxin mechanisms and environmental monitoring of harmful algal blooms.
• Drug Discovery: A lead compound or chemical probe for developing novel therapeutics targeting PKC-related pathways.
• Academic Research: Fundamental studies in marine natural product chemistry, biosynthesis, and molecular pharmacology.

Basic Information

Product Name	Debromoaplysiatoxin
CAS No.	52423-28-6
Molecular Formula	C32H47BrO10
Molecular Weight	671.62 g/mol
Synonyms	Debromoaplysiatoxin; Aplysiatoxin, debromo-; Debromoaplysiatoxin (DBAT); 15,16-Didebromoaplysiatoxin; 32-Hydroxy-15,16-didebromo-12-O-deacetyl-19-deoxo-19-oxoaplysiatoxin; Marine cyanotoxin; PKC activator (debromo); CAS 52423-28-6
EINECS	Contact for details

Quality Control

Our Debromoaplysiatoxin is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and reliability for research applications. Each lot undergoes comprehensive analytical characterization using techniques including HPLC, NMR, and MS to confirm identity and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all relevant specifications. We support research-grade standards and can discuss custom purity requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. For short-term storage, keep at 2-8°C. The product is light-sensitive and should be handled under appropriate conditions to maintain stability. Allow the vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Research Grade)
Purity (HPLC)	≥ 98% (High-Purity Grade)
Water Content (KF)	≤ 1.0%
Solubility	Soluble in DMSO, ethanol, methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.