Description

Trimethylphosphoramide is a versatile organophosphorus compound with a CAS number of 52420-88-9, serving as a key intermediate and reagent in advanced chemical synthesis. Its value lies in its unique chemical structure, which makes it an effective ligand, catalyst component, and building block for more complex molecules. This product is essential for research and development laboratories, pharmaceutical manufacturers, and agrochemical producers seeking to develop new active ingredients and specialty materials.

Application

• As a ligand or catalyst component in transition metal-catalyzed reactions, including cross-coupling and polymerization processes.
• As a key chemical intermediate in the synthesis of pharmaceuticals and agrochemicals.
• In organic synthesis as a phosphorylating or aminating agent for the modification of complex molecules.
• For research and development of novel flame retardants and plastic additives.
• As a potential precursor in the production of specialty polymers and advanced materials.
• In analytical chemistry as a derivatization agent or a standard for method development.

Basic Information

Product Name	Trimethylphosphoramide
CAS No.	52420-88-9
Molecular Formula	C3H12N3OP
Molecular Weight	137.12 g/mol
Synonyms	Phosphoric Triamide, N,N,N-Trimethyl-; Trimethylphosphoric Triamide; N,N,N-Trimethylphosphoramide; TMPA; Phosphoramide, N,N,N-trimethyl-; Trimethyl Phosphorotriamide; Hexamethylphosphoramide (HMPA) analogue
EINECS	257-902-2

Quality Control

Our Trimethylphosphoramide is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is subjected to comprehensive analytical testing, including assay, identity confirmation, and impurity profiling. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting compliance with agreed specifications. We support our clients' regulatory needs with full traceability and documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flames. Due to its potential sensitivity, it is recommended to store under an inert atmosphere for long-term stability and to minimize contact with moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (GC or HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.