Description

(R)-(+)-α-Methyl-2-Naphthalenemethanol CAS NO 52193-85-8 is a high-purity chiral alcohol derivative of 2-methylnaphthalene, serving as a critical chiral building block and resolving agent in advanced organic synthesis. Its value lies in its ability to impart stereochemical control, enabling the production of enantiomerically pure intermediates for pharmaceuticals and specialty chemicals. This compound is essential for research and development chemists, process chemists, and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries who require high optical purity for asymmetric synthesis and chiral separations.

Application

• Chiral Auxiliary/Resolving Agent: Used in the resolution of racemic mixtures and as a chiral auxiliary in asymmetric synthesis to control stereochemistry.
• Pharmaceutical Intermediate: A key building block in the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and cardiovascular drugs.
• Agrochemical Synthesis: Employed in the development of chiral pesticides and herbicides where specific stereoisomers exhibit enhanced biological activity.
• Ligand Precursor: Serves as a precursor for chiral ligands used in asymmetric catalysis, such as in hydrogenation or oxidation reactions.
• Fine Chemical Production: Utilized in the manufacture of specialty chemicals, flavors, and fragrances requiring specific optical isomers.
• Academic & Industrial R&D: A valuable tool for methodological development in organic chemistry and process optimization studies.

Basic Information

Item	Detail
Product Name	(R)-(+)-α-Methyl-2-Naphthalenemethanol
CAS No.	52193-85-8
Molecular Formula	C₁₂H₁₂O
Molecular Weight	172.22 g/mol
Synonyms	(R)-(+)-1-(2-Naphthyl)ethanol; (R)-1-(Naphthalen-2-yl)ethanol; (R)-α-Methyl-2-naphthalenemethanol; (R)-2-(1-Hydroxyethyl)naphthalene; (+)-(R)-1-(2-Naphthyl)ethyl alcohol; (R)-1-(2-Naphthalenyl)ethanol; (R)-2-Naphthylethanol
EINECS	Contact for details

Quality Control

Every batch of (R)-(+)-α-Methyl-2-Naphthalenemethanol is produced under strict quality management systems. We employ advanced analytical techniques, including chiral HPLC, GC, and NMR, to ensure high chemical and optical purity (typically >98% ee). Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing identity, purity, and specific rotation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Optical Purity (Chiral HPLC)	≥ 98.0% ee
Specific Rotation [α]₂₀ᴰ	+40° to +44° (c=1 in CHCl₃)
Melting Point	70°C - 74°C
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.