Description

(1R,6R)-5-Hydroxy-3-Methyl-7-Oxabicyclo[4.1.0]Hept-3-En-2-One is a high-purity, chiral bicyclic lactone compound that serves as a critical synthetic intermediate and building block in advanced organic synthesis. Its unique stereochemistry and functional group arrangement make it a valuable precursor for the development of complex, biologically active molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly for applications requiring precise stereochemical control.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of active pharmaceutical ingredients (APIs), especially in the development of prostaglandin analogs and other bioactive compounds.
• Fine Chemical Synthesis: Used in the preparation of complex natural products, fragrances, and specialty chemicals where its oxabicycloheptene core structure is required.
• Asymmetric Catalysis Research: Serves as a valuable substrate or ligand precursor in the development and testing of new asymmetric catalytic reactions.
• Agrochemical Development: Potential intermediate in the synthesis of novel, stereochemically defined agrochemicals and plant growth regulators.
• Material Science Research: Can be utilized as a monomer or cross-linking agent in the development of specialized polymers with unique thermal or optical properties.

Basic Information

Product Name	(1R,6R)-5-Hydroxy-3-Methyl-7-Oxabicyclo[4.1.0]Hept-3-En-2-One
CAS No.	52146-62-0
Molecular Formula	C8H10O3
Molecular Weight	154.16 g/mol
Synonyms	(1R,6R)-5-Hydroxy-3-methyl-7-oxabicyclo[4.1.0]hept-3-en-2-one; 5-Hydroxy-3-methyl-7-oxabicyclo[4.1.0]hept-3-en-2-one, (1R,6R)-; (1R,6R)-rel-5-Hydroxy-3-methyl-7-oxabicyclo[4.1.0]hept-3-en-2-one; Bicyclic Lactone Derivative; 7-Oxabicyclo[4.1.0]hept-3-en-2-one derivative
EINECS	Contact for details

Quality Control

Our (1R,6R)-5-Hydroxy-3-Methyl-7-Oxabicyclo[4.1.0]Hept-3-En-2-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for research and pharmaceutical development. Certificates of Analysis (COA) detailing identity, purity, and chiral excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The container should be kept tightly sealed to protect the contents from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.