Description

1,4-Dibromobutan-2-One is a versatile brominated ketone building block of significant importance in advanced organic synthesis. Its high reactivity, particularly as an alkylating agent, makes it a critical intermediate for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, where it is used to develop active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of various active pharmaceutical ingredients (APIs), including potential candidates for therapeutic agents.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and other crop protection chemicals, leveraging its alkylation properties.
• Organic Synthesis Reagent: Serves as a versatile reagent for introducing dibromoalkyl groups in complex organic molecules, facilitating carbon chain elongation and functionalization.
• Material Science Research: Employed in the development of novel polymers, liquid crystals, and other advanced materials requiring specific brominated precursors.
• Cross-coupling Reactions: Acts as a substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to create complex biaryl and other structures.
• Heterocyclic Chemistry: A valuable precursor for the synthesis of various nitrogen- and oxygen-containing heterocycles, which are core structures in many bioactive compounds.

Basic Information

Product Name	1,4-Dibromobutan-2-One
CAS No.	52011-50-4
Molecular Formula	C4H6Br2O
Molecular Weight	229.90 g/mol
Synonyms	1,4-Dibromo-2-butanone; sym-Dibromoacetone; α,γ-Dibromoacetone; 2-Butanone, 1,4-dibromo-; Dibromoacetone; 1,4-Dibromobutanone; Acetone, dibromo-; NSC 60548
EINECS	257-599-7

Quality Control

Our 1,4-Dibromobutan-2-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of our global B2B clients. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to ensure full traceability and compliance with your internal specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, open flames, and incompatible materials such as strong bases and reducing agents. Due to its light-sensitive nature, containers should be amber-colored or stored in light-resistant packaging.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.