Description

4-Chloro-1-Butyne is a versatile halogenated alkyne building block with significant synthetic utility. Its unique structure, featuring both a terminal alkyne and a reactive chloroalkyl group, makes it a valuable intermediate for constructing complex molecular frameworks. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical sectors for applications in cross-coupling reactions, cycloadditions, and the synthesis of heterocycles.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs) and novel drug candidates.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and plant growth regulators.
• Material Science Research: Serves as a monomer or precursor for specialty polymers and advanced organic materials.
• Organic Synthesis: Employed in Sonogashira coupling, click chemistry, and other palladium-catalyzed cross-coupling reactions.
• Chemical Research: A fundamental reagent for exploring new synthetic methodologies and constructing complex organic molecules in academic and industrial R&D.

Basic Information

Product Name	4-Chloro-1-Butyne
CAS No.	51908-64-6
Molecular Formula	C₄H₅Cl
Molecular Weight	88.54 g/mol
Synonyms	1-Butyne, 4-chloro-; 4-Chlorobut-1-yne; 4-Chlorobutyne; But-1-yn-4-yl chloride; 1-Chloro-3-butyne; 4-Chloro-1-butyne
EINECS	Contact for details

Quality Control

Our 4-Chloro-1-Butyne is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including GC, NMR, and impurity profiling, to ensure high purity and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee compliance with your research and production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials. Due to its highly volatile nature, containers must be kept tightly sealed and handled with appropriate precautions to prevent evaporation and buildup of vapors. Recommended storage temperature: 2-8°C.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.