Description

3-[(E)-2-Nitroeth-1-Enyl]-1H-Indole is a specialized nitrovinyl indole derivative, a versatile chemical building block prized for its unique molecular architecture. This compound matters for its role as a key synthetic intermediate in the development of complex heterocyclic molecules and active pharmaceutical ingredients (APIs). It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for synthesis and process development.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel indole-based drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its heterocyclic core for biological activity.
• Organic Synthesis Building Block: A valuable reagent for constructing complex molecular frameworks in medicinal and synthetic chemistry.
• Material Science Research: Investigated for the development of organic semiconductors, dyes, and photoresponsive materials.
• Academic & R&D Laboratories: Employed in fundamental chemical research and method development for nitroalkene chemistry.

Basic Information

Product Name	3-[(E)-2-Nitroeth-1-Enyl]-1H-Indole
CAS No.	51870-94-1
Molecular Formula	C10H8N2O2
Molecular Weight	188.18 g/mol
Synonyms	(E)-2-(1H-Indol-3-yl)-1-nitroethene; 3-[(E)-2-Nitrovinyl]-1H-indole; 3-(2-Nitrovinyl)indole; 1H-Indole-3-acetaldehyde, 2-nitro-; β-(3-Indolyl)-β-nitroethylene; 3-(2-Nitroethenyl)-1H-indole; 2-(1H-Indol-3-yl)-1-nitroethylene
EINECS	Contact for details

Quality Control

Our 3-[(E)-2-Nitroeth-1-Enyl]-1H-Indole is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with key parameters including assay by HPLC, identification by FT-IR and NMR, and impurity profiling. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply for critical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This product is easily oxidized (store under inert atmosphere) and is light-sensitive (store away from light). Keep away from heat, sparks, and open flame. For long-term storage, consider storage under an inert gas such as nitrogen or argon.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.