Description

1-(3-Methoxyphenyl)-1H-Imidazole-2-Thiol is a specialized heterocyclic organic compound featuring a methoxyphenyl-substituted imidazole core with a thiol functional group. This unique structure makes it a valuable building block and intermediate in advanced organic synthesis, particularly for the development of pharmaceuticals and agrochemicals. It is primarily sought by R&D chemists and process development teams in the pharmaceutical, agrochemical, and fine chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and enzyme inhibitors.
• Agrochemical Synthesis: Serves as a core structure for developing novel fungicides, herbicides, and plant growth regulators due to its bioactive imidazole-thiol moiety.
• Ligand and Catalyst Development: Utilized in coordination chemistry to create chelating ligands for metal catalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Investigated as a monomer or additive for creating specialized polymers, coatings, and electronic materials with unique properties.
• Chemical Biology Probe: Used in research to develop molecular probes for studying biological pathways and protein interactions.

Basic Information

Product Name	1-(3-Methoxyphenyl)-1H-Imidazole-2-Thiol
CAS No.	51581-49-8
Molecular Formula	C10H10N2OS
Molecular Weight	206.26 g/mol
Synonyms	3-Methoxy-1H-imidazole-2-thiol, 1-phenyl derivative; 1-(3-Methoxyphenyl)-2-mercaptoimidazole; 2-Mercapto-1-(3-methoxyphenyl)imidazole; 1-(m-Methoxyphenyl)imidazole-2-thiol; 51581-49-8; 1H-Imidazole-2-thiol, 1-(3-methoxyphenyl)-; NSC 403058
EINECS	Contact for details

Quality Control

Our 1-(3-Methoxyphenyl)-1H-Imidazole-2-Thiol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity, identity, and consistency, meeting the stringent requirements of research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity (typically by HPLC), identity (IR, NMR), and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized; for long-term storage, consider keeping under an inert atmosphere such as nitrogen or argon. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.