Description

S-Benzyl-Dl-Cysteine-2,3,3-D3 is a deuterium-labeled derivative of the amino acid cysteine, specifically designed for research and analytical applications. This compound is a crucial tool for internal standardization and metabolic pathway tracing in mass spectrometry-based studies, ensuring high accuracy and reproducibility. It is primarily utilized by pharmaceutical researchers, analytical chemists, and isotope labeling specialists working in drug metabolism and pharmacokinetics (DMPK), proteomics, and stable isotope tracer methodologies.

Application

• Internal Standard for LC-MS/MS: Used as a quantitative reference standard in bioanalytical method development for drug and metabolite analysis.
• Metabolic Pathway Tracing: Employed in stable isotope labeling studies to investigate cysteine metabolism and incorporation into proteins or glutathione.
• Proteomics Research: Serves as a building block for synthesizing deuterium-labeled peptides for mass spectrometry-based protein quantification.
• Pharmaceutical Development: Critical for accurate quantification in Absorption, Distribution, Metabolism, and Excretion (ADME) studies during preclinical and clinical phases.
• Isotope Dilution Mass Spectrometry (IDMS): Provides high-precision calibration for the analysis of biological samples, enhancing data reliability.
• Biochemical Research: Used in enzymatic studies and as a precursor for synthesizing other labeled biochemical compounds.

Basic Information

Product Name	S-Benzyl-Dl-Cysteine-2,3,3-D3
CAS No.	51494-04-3
Molecular Formula	C10H10D3NO2S
Molecular Weight	214.30 g/mol (approx.)
Synonyms	S-Benzyl-DL-cysteine-2,3,3-d3; (R,S)-2-Amino-3-(benzylthio)-3,3-d2-2-d-propanoic acid; DL-Cysteine, S-benzyl-, 2,3,3-d3; Benzyl-DL-cysteine-d3; 3,3-Dideutero-2-deuterio-2-amino-3-(phenylmethylthio)propanoic acid; 2-Amino-3-(benzylthio)-3,3-d2-2-d-propanoic acid; S-Benzylcysteine-d3
EINECS	Contact for details

Quality Control

Our S-Benzyl-Dl-Cysteine-2,3,3-D3 is manufactured under strict quality systems to ensure the high chemical purity and isotopic enrichment required for sensitive analytical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing parameters such as chemical purity (by HPLC), isotopic purity (deuterium incorporation), and identity confirmation (by NMR and MS). We adhere to relevant industry standards for research chemicals, ensuring reliable and reproducible performance in your laboratory.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-content, NMR/MS)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.