Description

2-Amino-4,5-Dimethylthiophene-3-Carboxamide is a high-purity, versatile heterocyclic building block with significant synthetic utility. This compound is valued for its role as a key intermediate in the synthesis of complex organic molecules, particularly in pharmaceutical research and development. It is primarily sought after by fine chemical manufacturers and R&D laboratories engaged in creating novel active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of thiophene-based drug candidates, including potential kinase inhibitors and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the thiophene scaffold.
• Material Science Research: Serves as a building block for organic semiconductors, conductive polymers, and other functional materials due to its electron-rich thiophene core.
• Dye and Pigment Chemistry: Acts as an intermediate in the production of specialized dyes and organic pigments.
• Chemical Research & Development: Employed in academic and industrial labs for method development and the construction of complex heterocyclic libraries for screening.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs performing bespoke synthesis for client projects.

Basic Information

Product Name	2-Amino-4,5-Dimethylthiophene-3-Carboxamide
CAS No.	51486-04-5
Molecular Formula	C7H10N2OS
Molecular Weight	170.23 g/mol
Synonyms	3-Carbamoyl-4,5-dimethylthiophen-2-amine; 4,5-Dimethyl-2-aminothiophene-3-carboxamide; 2-Amino-4,5-dimethyl-3-thiophenecarboxamide; 4,5-Dimethyl-2-aminothiophene-3-carboxylic acid amide; 2-Amino-4,5-dimethyl-thiophene-3-carboxylic acid amide; 3-Cyano-4,5-dimethylthiophen-2-amine (related nitrile); 4,5-Dimethyl-2-aminothiophene-3-carbonitrile (related nitrile)
EINECS	Contact for details

Quality Control

Our 2-Amino-4,5-Dimethylthiophene-3-Carboxamide is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay (HPLC), related substances, and residual solvents. Our quality commitment supports applications requiring high-purity intermediates for GMP and non-GMP synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.