Description

2-Chloro-6-Methylergoline-8Beta-Acetonitrile Monomethanesulphonate is a high-purity, specialized ergoline derivative, a key intermediate in advanced pharmaceutical synthesis. This compound matters for its critical role in the research and development of novel therapeutic agents targeting neurological and cardiovascular systems. It is primarily needed by pharmaceutical R&D laboratories, contract manufacturing organizations (CMOs), and fine chemical suppliers engaged in the production of complex active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of complex ergot alkaloid derivatives and novel drug candidates.
• Neurological Research: Used in the development and study of compounds targeting serotonin and dopamine receptor pathways.
• Cardiovascular Drug Development: Serves as a precursor in research for agents affecting vascular tone and blood pressure regulation.
• Contract Synthesis: Supplied to CMOs for the custom manufacturing of proprietary APIs under cGMP conditions.
• Academic & Institutional Research: Utilized in university and institutional labs for pharmacological studies and method development.
• Reference Standard: Can be supplied as a high-purity standard for analytical method validation and quality control.

Basic Information

Product Name	2-Chloro-6-Methylergoline-8Beta-Acetonitrile Monomethanesulphonate
CAS No.	51473-23-5
Molecular Formula	C20H24ClN3O3S
Molecular Weight	421.94 g/mol
Synonyms	2-Chloro-6-methylergoline-8β-acetonitrile methanesulfonate; 2-Chloro-6-methyl-8β-cyanomethylergoline methanesulfonate; 2-Chloro-6-methyl-8β-(2-cyanoethyl)ergoline methanesulfonate; 2-Chloro-6-methyl-8β-(cyanomethyl)ergoline methanesulfonate; 2-Chloro-6-methyl-8β-(2-cyanoethyl)ergoline mesylate; 2-Chloro-6-methyl-8β-acetonitrile ergoline monomethanesulfonate; 8β-(2-Cyanoethyl)-2-chloro-6-methylergoline methanesulfonate
EINECS	Contact for details

Quality Control

Our 2-Chloro-6-Methylergoline-8Beta-Acetonitrile Monomethanesulphonate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for pharmaceutical intermediates. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.