Description

8-Chloroisoquinolin-3-Ol is a versatile and high-value heterocyclic building block, primarily utilized in advanced organic synthesis. Its unique molecular structure, featuring both chlorinated and hydroxylated functionalities, makes it a critical intermediate for constructing complex pharmacophores and functional materials. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and kinase inhibitors.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the isoquinoline scaffold contributes to biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in metal-catalyzed cross-coupling reactions and other catalytic processes.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport layers or light-emitting components, due to its conjugated system.
• Chemical Biology Probes: Utilized to develop molecular probes for studying enzyme function and biological pathways within academic and industrial research settings.
• Fine Chemical Production: Acts as a building block for manufacturing dyes, pigments, and other performance chemicals requiring specific heterocyclic architectures.

Basic Information

Product Name	8-Chloroisoquinolin-3-Ol
CAS No.	51463-18-4
Molecular Formula	C9H6ClNO
Molecular Weight	179.60 g/mol
Synonyms	3-Hydroxy-8-chloroisoquinoline; 8-Chloro-3-hydroxyisoquinoline; 8-Chloroisoquinolin-3-ol; 8-Chloro-3-isoquinolinol; 8-Chloro-3-isoquinolin-3-ol; 51463-18-4; 8-Chloro-3-isoquinolinol; 8-Chloro-3-isoquinolin-3-one (tautomer)
EINECS	Contact for details

Quality Control

Our 8-Chloroisoquinolin-3-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.