Description

3(2H)-Isoquinolinone, 6-Fluoro- CAS NO 51463-15-1 is a specialized fluorinated heterocyclic compound belonging to the isoquinolinone class, serving as a critical synthetic intermediate. Its value lies in the strategic incorporation of a fluorine atom, which can significantly alter the physicochemical and biological properties of target molecules. This high-purity building block is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries engaged in the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, particularly for central nervous system (CNS) and oncology targets, where the fluorine atom can enhance metabolic stability and bioavailability.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the fluorine substituent to improve efficacy and environmental profile.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the creation of advanced polymers and organic electronic materials with tailored properties.
• Chemical Biology Probe: Employed in medicinal chemistry for structure-activity relationship (SAR) studies and as a core scaffold in fragment-based drug discovery.
• Fluorine Chemistry Research: A valuable substrate for studying fluorination reactions and developing new methodologies in synthetic organic chemistry.

Basic Information

Item	Detail
Product Name	3(2H)-Isoquinolinone, 6-Fluoro-
CAS No.	51463-15-1
Molecular Formula	C9H6FNO
Molecular Weight	163.15 g/mol
Synonyms	6-Fluoro-3(2H)-isoquinolinone; 6-Fluoro-1H-isoquinolin-3-one; 6-Fluoro-3-hydroxyisoquinoline; 6-Fluoro-3-isoquinolinol; 6-Fluoro-3-isoquinolinone; 6-Fluoro-1,2-dihydro-3H-isoquinolin-3-one; 6-Fluoro-2,3-dihydroisoquinolin-1-one
EINECS	Contact for details

Quality Control

Our 3(2H)-Isoquinolinone, 6-Fluoro- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided for full traceability and quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.