Description

(S)-(Tetrahydro-2H-Pyran-2-Yl)Methanol is a valuable chiral building block and intermediate in organic synthesis, characterized by its tetrahydro-2H-pyran ring and hydroxymethyl group. This compound is essential for the production of enantiomerically pure pharmaceuticals and fine chemicals, where its stereochemistry imparts critical biological activity and selectivity. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing active pharmaceutical ingredients (APIs), ligands, and complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of enantiomerically pure drugs and active pharmaceutical ingredients (APIs).
• Asymmetric Catalyst Ligand: Used in the preparation of chiral ligands for transition metal catalysis in asymmetric synthesis.
• Agrochemical Synthesis: Serves as a building block for creating chiral herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances requiring specific stereochemistry.
• Academic & Industrial Research: A versatile reagent for methodological development in organic chemistry and medicinal chemistry research.
• Material Science Precursor: Potential use in synthesizing chiral polymers or functional materials.

Basic Information

Product Name	(S)-(Tetrahydro-2H-Pyran-2-Yl)Methanol
CAS No.	51450-44-3
Molecular Formula	C6H12O2
Molecular Weight	116.16 g/mol
Synonyms	(S)-(-)-Tetrahydro-2H-pyran-2-methanol; (S)-(-)-2-(Hydroxymethyl)tetrahydro-2H-pyran; (S)-Tetrahydro-2H-pyran-2-ylmethanol; (S)-2-(Hydroxymethyl)tetrahydropyran; (S)-THP-Methanol; (S)-Tetrahydro-2-pyranylmethanol; (2S)-Oxan-2-ylmethanol; (S)-(-)-2-Hydroxymethyltetrahydropyran
EINECS	Contact for details

Quality Control

Our (S)-(Tetrahydro-2H-Pyran-2-Yl)Methanol is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including chiral purity determination by HPLC, to meet the exacting standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and specific impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in secondary packaging or amber glass/vessels for long-term storage.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.