Description

7-Hydroxy-3-(1-Phenyl-1H-Pyrazol-4-Yl)-2-Trifluoromethyl-Chromen-4-One is a high-value, fluorinated chromenone derivative that serves as a critical advanced intermediate in modern synthetic chemistry. Its unique molecular architecture, featuring a trifluoromethyl group and a pyrazole moiety, makes it an essential building block for developing novel compounds with enhanced biological activity and material properties. This product is primarily sought by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating next-generation active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for targeting central nervous system (CNS) disorders, inflammatory diseases, and oncology applications.
• Agrochemical Research: Used in developing new-generation pesticides and herbicides, where the trifluoromethyl group can improve metabolic stability and bioavailability.
• Material Science: Serves as a building block for organic light-emitting diodes (OLEDs) and other advanced electronic materials due to its conjugated chromenone core.
• Chemical Biology Probe: Utilized as a scaffold or fluorescent tag in biochemical assays and diagnostic research.
• Academic & Contract Research: Employed in universities and CROs (Contract Research Organizations) for methodological studies in heterocyclic and fluoroorganic chemistry.
• Custom Synthesis: A starting material for the contract manufacturing of complex, proprietary molecules for various industrial applications.

Basic Information

Product Name	7-Hydroxy-3-(1-Phenyl-1H-Pyrazol-4-Yl)-2-Trifluoromethyl-Chromen-4-One
CAS No.	51412-01-2
Molecular Formula	C20H13F3N2O3
Molecular Weight	386.33 g/mol
Synonyms	7-Hydroxy-3-(1-phenyl-1H-pyrazol-4-yl)-2-(trifluoromethyl)-4H-chromen-4-one; 2-Trifluoromethyl-7-hydroxy-3-(1-phenyl-1H-pyrazol-4-yl)chromone; 4H-1-Benzopyran-4-one, 7-hydroxy-3-(1-phenyl-1H-pyrazol-4-yl)-2-(trifluoromethyl)-; 7-Hydroxy-3-(1-phenylpyrazol-4-yl)-2-trifluoromethylchromen-4-one; Fluorinated Chromone-Pyrazole Hybrid; 51412-01-2
EINECS	Contact for details

Quality Control

Our production of 7-Hydroxy-3-(1-Phenyl-1H-Pyrazol-4-Yl)-2-Trifluoromethyl-Chromen-4-One adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our quality system is designed to support cGMP compliance for pharmaceutical applications and meets the rigorous standards required for global regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light). Keep away from heat, sparks, and open flame. For long-term storage, consider inert gas purging to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.