Description

2-Trifluoromethylindole is a high-value fluorinated indole derivative, serving as a critical building block in advanced organic synthesis. Its unique trifluoromethyl group imparts enhanced metabolic stability and lipophilicity, making it indispensable for creating novel compounds with targeted properties. This intermediate is primarily sought after by pharmaceutical and agrochemical research and development teams for the synthesis of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in oncology, CNS, and anti-inflammatory research.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where the CF3 group can improve biological activity and environmental persistence.
• Material Science Precursor: Employed in the synthesis of specialized organic electronic materials and functional dyes.
• Fluorine Chemistry Research: Serves as a standard substrate for studying fluorination reactions and the effects of the trifluoromethyl group on indole chemistry.
• Ligand and Catalyst Development: Utilized to construct complex ligands for asymmetric catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	2-Trifluoromethylindole
CAS No.	51310-54-4
Molecular Formula	C9H6F3N
Molecular Weight	185.15 g/mol
Synonyms	2-(Trifluoromethyl)-1H-indole; 1H-Indole, 2-(trifluoromethyl)-; 2-Trifluoromethyl-1H-indole; Indole, 2-trifluoromethyl-; α,α,α-Trifluoro-2-indolylmethane; 2-CF3-Indole
EINECS	Contact for details

Quality Control

Our 2-Trifluoromethylindole is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, confirming compliance with customer specifications and industry best practices.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.