Description

Tetramethylurea-D12 CAS NO 51219-89-7 is a fully deuterated isotopologue of tetramethylurea, where all twelve hydrogen atoms are replaced by deuterium. This high isotopic purity makes it an invaluable tool for advanced spectroscopic studies, particularly in nuclear magnetic resonance (NMR) spectroscopy, where it serves as a non-interfering solvent or internal standard. It is essential for researchers and analytical laboratories in pharmaceutical development, materials science, and academic research requiring precise molecular structure elucidation without proton signal interference.

Application

• NMR Spectroscopy Solvent: Used as a deuterated solvent for analyzing compounds soluble in polar aprotic solvents, providing a clean background free of proton signals.
• Internal Standard for Quantitative NMR (qNMR): Acts as a precise internal standard for concentration determination and purity analysis of pharmaceutical compounds and complex molecules.
• Mechanistic Studies in Chemistry: Employed in reaction kinetics and mechanistic investigations where tracking deuterium labels is crucial, especially in organometallic and catalytic research.
• Polymer and Materials Science Research: Utilized in the analysis of polymer structures and dynamics, and as a solvent for processing specialized materials where protonated solvents are undesirable.
• Pharmaceutical Impurity Profiling: Aids in the structural identification of low-level impurities and degradants in active pharmaceutical ingredients (APIs) using high-resolution NMR techniques.
• Metabolomics and Biomolecular NMR: Supports research in metabolomics and the study of biomolecules by providing a compatible deuterated environment for sample preparation.

Basic Information

Product Name	Tetramethylurea-D12
CAS No.	51219-89-7
Molecular Formula	C5D12N2O
Molecular Weight	128.22 g/mol
Synonyms	Perdeuterotetramethylurea; TMU-D12; N,N,N',N'-Tetramethylurea-d12; 1,1,3,3-Tetramethylurea-d12; Tetramethylurea (D12); Urea-d12, N,N,N',N'-tetramethyl-; Deuterated TMU; Hexadeutero-bis(dideuteromethyl)urea
EINECS	Contact for details

Quality Control

Our Tetramethylurea-D12 is produced under stringent conditions to ensure exceptional isotopic and chemical purity, critical for sensitive analytical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing key parameters such as isotopic enrichment (D-atom %), chemical purity, and solvent residues. We adhere to rigorous internal quality standards to guarantee batch-to-batch consistency and reliability for your research and development needs.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. Keep away from strong acids and strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Deuterium Content (NMR)	≥ 99.0 atom % D
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.