Description

[2S,4S,(+)]-3,4-Dihydro-2-Phenyl-2H-1-Benzopyran-4-Ol CAS NO 51196-83-9 is a high-purity chiral chroman derivative, a key intermediate in advanced organic synthesis. This compound matters for its role in constructing complex molecular architectures with precise stereochemistry, which is critical for developing active pharmaceutical ingredients (APIs) and fine chemicals. It is needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors seeking reliable, high-quality building blocks for their synthetic workflows.

Application

• Pharmaceutical Intermediate: A crucial chiral building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and cardiovascular research.
• Asymmetric Synthesis: Used as a starting material or ligand precursor in catalytic asymmetric reactions to induce enantioselectivity.
• Fine Chemical Production: Serves as a key intermediate in the manufacture of complex agrochemicals, flavors, and fragrances.
• Academic & R&D: Employed in university and corporate research laboratories for methodological studies in organic and medicinal chemistry.
• Process Chemistry: Utilized in scale-up and process optimization for the commercial production of chiral target molecules.

Basic Information

Product Name	[2S,4S,(+)]-3,4-Dihydro-2-Phenyl-2H-1-Benzopyran-4-Ol
CAS No.	51196-83-9
Molecular Formula	C15H14O2
Molecular Weight	226.27 g/mol
Synonyms	(+)-cis-2-Phenyl-4-hydroxychromane; (2S,4S)-2-Phenylchroman-4-ol; (2S,4S)-4-Hydroxy-2-phenyl-3,4-dihydro-2H-chromene; (2S,4S)-2-Phenyl-3,4-dihydro-2H-1-benzopyran-4-ol; (2S,4S)-2-Phenyl-4-chromanol; (2S-cis)-2-Phenyl-4-hydroxy-3,4-dihydro-2H-1-benzopyran; (+)-(2S,4S)-4-Hydroxy-2-phenylchroman
EINECS	Contact for details

Quality Control

Our [2S,4S,(+)]-3,4-Dihydro-2-Phenyl-2H-1-Benzopyran-4-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with exacting standards for research and industrial use. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee identity, purity, and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is light-sensitive and easily oxidized; for long-term storage, consider keeping under an inert atmosphere such as nitrogen or argon to maintain optimal purity and stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.