Description

1-Cyanomethylene-6,7-Dimethoxy-1,2,3,4-Tetrahydroisoquinoline is a versatile and synthetically valuable heterocyclic building block. This compound is a key intermediate in the synthesis of complex alkaloids and other pharmacologically active molecules, prized for its reactive cyanomethylene group and tetrahydroisoquinoline core. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of new chemical entities, particularly for central nervous system (CNS) and cardiovascular targets.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of isoquinoline-based alkaloids and novel drug candidates.
• Organic Synthesis Building Block: Used in cyclization, alkylation, and other C-C bond-forming reactions to construct complex heterocyclic frameworks.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies for developing compounds with potential therapeutic effects.
• Chemical Reference Standard: Serves as a high-purity analytical standard for quality control and method development in R&D laboratories.
• Agrochemical Research: Investigated as an intermediate for developing new crop protection agents and pesticides.

Basic Information

Product Name	1-Cyanomethylene-6,7-Dimethoxy-1,2,3,4-Tetrahydroisoquinoline
CAS No.	51054-41-2
Molecular Formula	C₁₃H₁₄N₂O₂
Molecular Weight	230.26 g/mol
Synonyms	6,7-Dimethoxy-1-cyanomethylene-1,2,3,4-tetrahydroisoquinoline; 1-(Cyanomethylene)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline; 6,7-Dimethoxy-1-(cyanomethylene)-1,2,3,4-tetrahydroisoquinoline; 1,2,3,4-Tetrahydro-6,7-dimethoxy-1-isoquinolineacetonitrile; 1-Cyanomethylene-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline; Tetrahydroisoquinoline cyanomethylene derivative
EINECS	Contact for details

Quality Control

Our 1-Cyanomethylene-6,7-Dimethoxy-1,2,3,4-Tetrahydroisoquinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.