Description

Diethyl-2,2,2,2',2',2'-D6-Amine is a deuterium-labeled analog of diethylamine, where six hydrogen atoms are replaced with the stable isotope deuterium, offering a non-radioactive tracer for advanced analytical and research applications. This high-purity labeled compound is essential for mechanistic studies, metabolic pathway tracing, and as an internal standard in quantitative mass spectrometry, providing unmatched accuracy and reliability. It is a critical reagent for researchers and analytical laboratories in the pharmaceutical, agrochemical, and academic sectors who require precise isotopic labeling for their investigations.

Application

• Internal Standard for Quantitative Analysis: Used as a deuterated internal standard in LC-MS and GC-MS for the accurate quantification of diethylamine and related compounds in complex matrices.
• Metabolic and Pharmacokinetic Studies: Serves as a stable isotopic tracer to study the absorption, distribution, metabolism, and excretion (ADME) of amine-containing pharmaceuticals and agrochemicals.
• Mechanistic Reaction Studies: Employed in reaction mechanism elucidation, including kinetic isotope effect (KIE) studies, to understand chemical and biochemical pathways.
• NMR Spectroscopy: Acts as a useful probe in nuclear magnetic resonance (NMR) spectroscopy due to the distinct properties of deuterium nuclei.
• Chemical Synthesis: Utilized as a labeled building block in the synthesis of more complex deuterated molecules for research and development.
• Environmental and Forensic Analysis: Applied in trace analysis and detection methods where isotopic labeling enhances specificity and reduces background interference.

Basic Information

Product Name	Diethyl-2,2,2,2',2',2'-D6-Amine
CAS No.	51045-01-3
Molecular Formula	C4D6H5N
Molecular Weight	79.15 g/mol
Synonyms	Diethylamine-d6; (C2D5)2NH; N,N-Diethylamine-d6; Deuterated Diethylamine; Diethylamine (hexadeutero); Diethyl-d10-amine; DEA-d6; N-Ethylethanamine-d6
EINECS	Contact for details

Quality Control

Every batch of Diethyl-2,2,2,2',2',2'-D6-Amine is manufactured and tested under strict quality management systems to ensure the highest isotopic and chemical purity for research applications. Our products undergo rigorous quality testing, including NMR, GC-MS, and HPLC analysis, to ensure compliance with exacting specifications. A comprehensive Certificate of Analysis (COA) detailing isotopic enrichment, chemical purity, and analytical results is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Due to its highly volatile and hygroscopic nature, this product should be stored in a cool, dry, and well-ventilated place. For long-term stability, storage under an inert atmosphere (e.g., nitrogen or argon) in a refrigerator (2-8°C) is recommended. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Isotopic Enrichment (D)	≥ 98 atom % D
Chemical Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.