Description

1-Bromo-1-Methylcyclopropane is a versatile cyclopropane derivative, a key building block in advanced organic synthesis. Its unique structure, featuring a bromine atom on a quaternary carbon, makes it a valuable precursor for introducing the strained and pharmacologically interesting cyclopropyl group into target molecules. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to develop novel compounds with enhanced properties.

Application

• Pharmaceutical Intermediates: Serves as a critical synthon for the synthesis of active pharmaceutical ingredients (APIs) containing cyclopropyl motifs, which are common in various therapeutic agents.
• Agrochemical Synthesis: Used in the research and production of novel pesticides and herbicides, where the cyclopropyl group can enhance biological activity and stability.
• Material Science Research: Acts as a monomer or cross-linking agent in the development of specialized polymers and advanced materials with unique mechanical or chemical properties.
• Organic Synthesis Reagent: Employed in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Negishi) and nucleophilic substitution reactions to construct complex molecular architectures.
• Ligand and Catalyst Development: Utilized as a precursor for synthesizing specialized ligands and organometallic catalysts used in asymmetric synthesis.
• Flavor and Fragrance Industry: Potential intermediate for the synthesis of certain aroma chemicals that incorporate cyclopropane rings.

Basic Information

Product Name	1-Bromo-1-Methylcyclopropane
CAS No.	50915-27-0
Molecular Formula	C5H9Br
Molecular Weight	149.03 g/mol
Synonyms	(1-Bromo-1-methyl)cyclopropane; 1-Methyl-1-bromocyclopropane; Bromomethylcyclopropane; Cyclopropane, 1-bromo-1-methyl-; 1-Bromomethylcyclopropane; (Bromomethyl)cyclopropane; 1-Bromo-1-methyl-cyclopropane
EINECS	Contact for details

Quality Control

Our 1-Bromo-1-Methylcyclopropane is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC, NMR, and Karl Fischer titration, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment ensures the material meets the stringent requirements for research and process development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place, away from heat sources and incompatible materials such as strong acids and strong oxidizing agents. Recommended storage temperature is 2-8°C for extended stability. Keep container tightly sealed when not in use to prevent moisture absorption and volatility loss.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Density (at 20°C)	~1.35 g/mL
Boiling Point	~125-130°C
Refractive Index (n20D)	~1.480

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.