Description

Ephedrine Hemihydrate is a pharmaceutical-grade alkaloid salt, recognized for its role as a key intermediate and active pharmaceutical ingredient (API). Its significance lies in its potent sympathomimetic properties, making it a critical component in the synthesis of various therapeutic agents. This compound is essential for manufacturers in the pharmaceutical, fine chemical, and research sectors requiring a high-purity building block for decongestants, bronchodilators, and central nervous system stimulants.

Application

• Pharmaceutical API Synthesis: Primary use as an active pharmaceutical ingredient in the manufacture of prescription and over-the-counter medications for asthma, bronchitis, and nasal congestion.
• Decongestant Formulations: A key component in oral tablets, syrups, and nasal sprays designed for temporary relief of sinus pressure and congestion.
• Bronchodilator Production: Utilized in the production of drugs that relax and open air passages to the lungs to treat breathing disorders.
• Chemical Intermediate: Serves as a crucial chiral intermediate in the multi-step synthesis of more complex pharmaceutical compounds and fine chemicals.
• Research & Development: Used in biochemical research, pharmacological studies, and as a reference standard in analytical laboratories.
• Veterinary Pharmaceuticals: Incorporated into certain veterinary medicinal products for respiratory conditions in animals.

Basic Information

Product Name	Ephedrine Hemihydrate
CAS No.	50906-05-3
Molecular Formula	C10H15NO · ½H2O
Molecular Weight	174.24 g/mol (anhydrous basis)
Synonyms	(-)-Ephedrine Hemihydrate; L-Ephedrine Hemihydrate; (1R,2S)-(-)-Ephedrine Hemihydrate; Ephedrine Monohydrate (common name); 2-Methylamino-1-phenylpropan-1-ol hemihydrate; Eryfed; Efedrin; Contact for additional trade names.
EINECS	Contact for details

Quality Control

Our Ephedrine Hemihydrate is produced and tested under strict quality management systems to meet the exacting standards of the pharmaceutical industry. We ensure compliance with relevant pharmacopoeial monographs, including USP and EP, where applicable. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles, available upon request to guarantee traceability and product integrity for your regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. Follow all applicable local, regional, and national regulations for storage of pharmaceutical substances.

Specification

Item	Specification
Appearance	White or almost white crystalline powder
Identification (IR)	Conforms to standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Specific Rotation	-33° to -36° (c=5 in H2O)
Water Content (KF)	4.0% - 5.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.