Description

6-Carboxyhexyl Triphenylphosphonium Bromide is a high-purity, functionalized phosphonium salt widely used as a key reagent in organic synthesis. Its primary value lies in its role as a versatile Wittig reagent for the synthesis of α,β-unsaturated carboxylic acids and esters, enabling the construction of complex molecular frameworks. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries, where precise carbon-carbon bond formation is critical.

Application

• Wittig Olefination Reactions: A crucial reagent for the synthesis of α,β-unsaturated carboxylic acids and their derivatives, forming valuable intermediates for active pharmaceutical ingredients (APIs).
• Pharmaceutical Intermediate Synthesis: Used in the production of prostaglandins, leukotrienes, and other bioactive molecules containing carboxylic acid functional groups.
• Agrochemical Manufacturing: Employed in the synthesis of complex organic molecules for crop protection agents and plant growth regulators.
• Liquid Crystal & Advanced Material Production: Serves as a building block for creating organic molecules with specific optical and electronic properties.
• Polymer Chemistry: Can be utilized to introduce carboxylic acid functionality into polymer chains for specialty polymers and coatings.
• Cross-Coupling & Catalysis: Acts as a precursor or ligand in various transition metal-catalyzed reactions.
• Peptide Modification: Used to introduce unsaturated linkages or specific side chains into peptide structures.
• Academic & Process R&D: A staple reagent in research laboratories for method development and scale-up studies in synthetic organic chemistry.

Basic Information

Product Name	6-Carboxyhexyl Triphenylphosphonium Bromide
CAS No.	50889-30-0
Molecular Formula	C25H28BrO2P
Molecular Weight	471.36 g/mol
Synonyms	6-Carboxyhexyltriphenylphosphonium Bromide; (6-Carboxyhexyl)triphenylphosphonium Bromide; 6-(Triphenylphosphonio)hexanoate Bromide; ω-Carboxyhexyltriphenylphosphonium Bromide; Hexanoic Acid, 6-(Triphenylphosphonio)-, Bromide; 6-(Triphenylphosphoniumyl)hexanoic Acid Bromide; Wittig Reagent for ω-Carboxyalkenes; TPHP-C6-COOH-Br
EINECS	Contact for details

Quality Control

Our 6-Carboxyhexyl Triphenylphosphonium Bromide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and KF titration for moisture content, to ensure it meets the high standards required for synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment, and custom synthesis to meet specific purity or packaging requirements is available.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.