Description

(2E)-3-(5-Bromo(2-Thienyl))Prop-2-Enoic Acid is a high-purity, synthetic organic compound featuring a brominated thiophene core conjugated to an acrylic acid moiety. This specific molecular architecture makes it a versatile and critical building block for advanced chemical synthesis, particularly in the development of novel pharmaceuticals and functional materials. It is primarily sought after by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in creating complex molecules for therapeutic and material science applications.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders, inflammation, or as kinase inhibitors.
• Organic Synthesis Building Block: Used in coupling reactions (e.g., Suzuki, Heck) to construct complex heterocyclic systems and conjugated polymers due to its reactive bromine and alkene functionalities.
• Material Science Research: Serves as a monomer or precursor for developing organic semiconductors, conductive polymers, and non-linear optical (NLO) materials.
• Agrochemical Development: Employed in the research and synthesis of novel crop protection agents and herbicides.
• Ligand and Catalyst Design: The thiophene and carboxylic acid groups make it useful for creating novel ligands for metal catalysis.
• Chemical Biology Probes: Used to develop molecular probes for studying biological processes and enzyme functions.

Basic Information

Product Name	(2E)-3-(5-Bromo(2-Thienyl))Prop-2-Enoic Acid
CAS No.	50868-68-3
Molecular Formula	C7H5BrO2S
Molecular Weight	233.08 g/mol
Synonyms	5-Bromo-2-thiopheneacrylic Acid; (E)-3-(5-Bromothiophen-2-yl)acrylic Acid; trans-3-(5-Bromo-2-thienyl)-2-propenoic Acid; 3-(5-Bromo-2-thienyl)propenoic Acid; 5-Bromothiophene-2-acrylic Acid; (2E)-3-(5-Bromothiophen-2-yl)prop-2-enoic Acid; 2-Thiopheneacrylic acid, 5-bromo-
EINECS	Contact for details

Quality Control

Our (2E)-3-(5-Bromo(2-Thienyl))Prop-2-Enoic Acid is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC, NMR, and IR spectroscopy, to verify identity and purity. Certificates of Analysis (COA) are available for every batch upon request, detailing all relevant specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	185 - 190 °C
Loss on Drying	≤ 1.0 %
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.