Description

1,3-Dimethylxanthine is a high-purity xanthine derivative, also known as theophylline-7-acetic acid, serving as a critical pharmaceutical intermediate and research chemical. Its primary commercial value lies in its role as a key precursor in the synthesis of active pharmaceutical ingredients (APIs) and as a reference standard for analytical and pharmacological studies. This compound is essential for manufacturers and research institutions in the pharmaceutical, biotechnology, and fine chemical sectors requiring reliable, high-quality intermediates for drug development and production.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of theophylline and related methylxanthine-based active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard and reagent in studies of adenosine receptor antagonism, phosphodiesterase inhibition, and bronchodilation mechanisms.
• Analytical Standard: Serves as a certified reference material (CRM) for quality control and method validation in HPLC, LC-MS, and other analytical techniques.
• Fine Chemical Synthesis: Employed as a versatile intermediate for the preparation of more complex xanthine derivatives and specialty chemicals.
• Metabolite Studies: Utilized in metabolic pathway research and the study of caffeine and theophylline metabolism in biological systems.

Basic Information

Product Name	1,3-Dimethylxanthine
CAS No.	50857-74-4
Molecular Formula	C7H8N4O2
Molecular Weight	180.16 g/mol
Synonyms	1,3-Dimethyl-2,6-dioxo-7H-purine; 1,3-Dimethyl-7H-purine-2,6-dione; Theophylline-7-acetic acid; 3,7-Dihydro-1,3-dimethyl-1H-purine-2,6-dione; 1,3-Dimethylxanthine; Paraxanthine impurity; 1,3-Dimethyluric acid (obsolete); DMX
EINECS	Contact for details

Quality Control

Our 1,3-Dimethylxanthine is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical intermediates and research chemicals. Certificates of Analysis (COA) detailing purity (typically ≥98% by HPLC), residual solvents, and related substances are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.