Description

5-Thiophen-2-Yl-3H-[1,2,3]Triazole-4-Carbonitrile is a heterocyclic organic compound featuring a fused triazole-thiophene core, serving as a versatile and high-value synthetic building block. Its molecular architecture makes it a critical intermediate for the development of novel pharmaceuticals, agrochemicals, and advanced materials. This compound is primarily sought by research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecules with targeted biological or functional properties.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system disorders, infectious diseases, and oncology.
• Agrochemical Research: Used in developing new generations of herbicides, fungicides, and insecticides due to its bioactive heterocyclic scaffold.
• Material Science: Serves as a monomer or functional unit in the creation of organic semiconductors, conductive polymers, and liquid crystals.
• Chemical Biology & Proteomics: Employed as a click chemistry reagent or a tagging moiety for bioconjugation and probe development.
• Academic & Contract Research: Essential for methodological studies in organic synthesis and medicinal chemistry within university and CRO laboratories.
• Dye & Pigment Industry: Potential intermediate for synthesizing specialized heterocyclic dyes and optical brighteners.

Basic Information

Product Name	5-Thiophen-2-Yl-3H-[1,2,3]Triazole-4-Carbonitrile
CAS No.	50710-07-1
Molecular Formula	C7H4N4S
Molecular Weight	176.20 g/mol
Synonyms	5-(Thiophen-2-yl)-1H-1,2,3-triazole-4-carbonitrile; 5-(2-Thienyl)-1H-1,2,3-triazole-4-carbonitrile; 2-Thienyl-1,2,3-triazole-4-carbonitrile; 4-Cyano-5-(2-thienyl)-1,2,3-triazole; 5-(2-Thienyl)-4-cyano-1,2,3-triazole; 1H-1,2,3-Triazole-4-carbonitrile, 5-(2-thienyl)-; 50710-07-1
EINECS	Contact for details

Quality Control

Our production of 5-Thiophen-2-Yl-3H-[1,2,3]Triazole-4-Carbonitrile adheres to stringent in-process controls and final batch analysis to ensure consistent high purity and chemical identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, related substances, and residual solvents. Our quality management system supports customization to meet specific client requirements, including research-grade and GMP-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive and hygroscopic; therefore, handling under an inert atmosphere is recommended for long-term storage or when working with large quantities.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.