Description

1H-Indole, 1-(Chloroacetyl)Octahydro-, trans- (9Ci) is a specialized indole derivative that serves as a crucial chiral building block and synthetic intermediate in advanced organic synthesis. Its value lies in its unique fused bicyclic structure and functional groups, which enable the construction of complex molecules with precise stereochemistry. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of active pharmaceutical ingredients (APIs), agrochemicals, and other fine chemicals where stereochemical control is paramount.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents, particularly for central nervous system (CNS) targets.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides that require specific stereoisomers for optimal biological activity.
• Asymmetric Catalysis Research: Serves as a substrate or ligand precursor in the development of new catalytic systems for stereoselective transformations.
• Fine Chemical Manufacturing: Employed in the synthesis of complex fragrance and flavor ingredients where structural complexity is desired.
• Academic & Process Chemistry: A valuable compound for methodological studies in organic synthesis and for scaling up novel synthetic routes.

Basic Information

Product Name	1H-Indole, 1-(Chloroacetyl)Octahydro-, trans- (9Ci)
CAS No.	50669-85-7
Molecular Formula	C12H18ClNO
Molecular Weight	227.73 g/mol
Synonyms	trans-1-(Chloroacetyl)octahydro-1H-indole; 1-(Chloroacetyl)octahydro-1H-indole, trans-; Octahydro-1-(chloroacetyl)-1H-indole, trans-; 1H-Indole, 1-(chloroacetyl)octahydro-, trans-; (3aR,7aR)-1-(2-Chloroacetyl)octahydro-1H-indole; (3aR,7aR)-1-(Chloroacetyl)octahydroindole; 1-(Chloroacetyl)hexahydro-1H-indole (related); trans-Octahydro-1-(chloroacetyl)indole
EINECS	Contact for details

Quality Control

Our 1H-Indole, 1-(Chloroacetyl)Octahydro-, trans- (9Ci) is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for research and process chemistry. A detailed Certificate of Analysis (COA) providing identity, purity, and impurity profile is supplied with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% de
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.