Description

5-Bromo-2-Chloromethyl-Benzo[B]Thiophene is a high-purity, multi-functional heterocyclic building block of significant importance in advanced organic synthesis. Its core value lies in its reactive chloromethyl and bromo substituents, which enable precise molecular construction for creating complex target structures. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries, serving as a critical precursor for active pharmaceutical ingredients (APIs), functional ligands, and novel organic electronic materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel therapeutic agents, particularly in kinase inhibitor and antiviral drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and plant growth regulators.
• Material Science Precursor: Serves as a building block for organic semiconductors, conductive polymers, and photoactive materials in OLED and OFET applications.
• Ligand and Catalyst Development: Employed in the synthesis of complex chelating ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Research: A versatile reagent for methodological studies in cross-coupling reactions, nucleophilic substitutions, and heterocyclic chemistry.
• Custom Synthesis: Provides a foundational structure for contract research organizations (CROs) and CDMOs to develop proprietary compounds for clients.

Basic Information

Product Name	5-Bromo-2-Chloromethyl-Benzo[B]Thiophene
CAS No.	50638-17-0
Molecular Formula	C9H6BrClS
Molecular Weight	261.56 g/mol
Synonyms	2-(Chloromethyl)-5-bromobenzo[b]thiophene; 5-Bromo-2-(chloromethyl)benzo[b]thiophene; 5-Bromo-2-chloromethyl-1-benzothiophene; Benzo[b]thiophene, 5-bromo-2-(chloromethyl)-; 5-Bromo-2-chloromethylbenzothiophene
EINECS	Contact for details

Quality Control

Every batch of 5-Bromo-2-Chloromethyl-Benzo[B]Thiophene is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure consistency and high purity. Our standard grade typically meets a purity specification of ≥97% (by HPLC), with detailed impurity profiling available. A comprehensive Certificate of Analysis (COA) documenting identity, purity, and related substances is provided with each shipment. We support cGMP and ISO 9001 compliant production for advanced applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.