Description

2-Bromofluorobenzene-D4 is a deuterated aromatic compound where four hydrogen atoms are replaced by deuterium, serving as a stable isotopologue of 2-bromofluorobenzene. This deuteration is critical for applications requiring non-radioactive isotopic labeling, such as internal standards in mass spectrometry and mechanistic studies in organic chemistry. It is an essential building block for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity, isotopically labeled intermediates for synthesis, analytical method development, and metabolic research.

Application

• Internal Standard for Quantitative Analysis: Used as a deuterated internal standard in GC-MS and LC-MS for the accurate quantification of bromofluorobenzene analogs and related compounds in complex matrices.
• Pharmaceutical Research: Serves as a labeled precursor or intermediate in the synthesis of deuterated drug candidates for pharmacokinetic, metabolic, and degradation pathway studies.
• Mechanistic Probes: Employed in reaction mechanism elucidation and isotope effect studies within organic and organometallic chemistry due to the kinetic isotope effect of deuterium.
• Agrochemical Development: Utilized in the research and development of labeled pesticides or herbicides to study environmental fate, metabolism, and residue analysis.
• NMR Spectroscopy: Acts as a useful solvent or analyte in nuclear magnetic resonance spectroscopy, benefiting from the absence of proton signals from the deuterated positions.
• Material Science: Potential use in the synthesis of specialty polymers or organic electronic materials where isotopic labeling is required to study structure-property relationships.

Basic Information

Item	Detail
Product Name	2-Bromofluorobenzene-D4
CAS No.	50592-35-3
Molecular Formula	C6H2D4BrF
Molecular Weight	179.02 g/mol (approx.)
Synonyms	1-Bromo-2-fluorobenzene-D4; o-Bromofluorobenzene-D4; 2-Fluorobromobenzene-D4; (2-Bromofluorobenzene)-d4; Deutero-o-bromofluorobenzene; Perdeuterated 2-Bromofluorobenzene (specific to D4); Bromo(fluoro)benzene-d4; Fluorobromobenzene-d4
EINECS	Contact for details

Quality Control

Our 2-Bromofluorobenzene-D4 is manufactured under strict quality systems to ensure high isotopic and chemical purity, which is paramount for analytical and synthetic applications. Each batch is characterized using advanced analytical techniques including NMR, GC-MS, and HPLC to confirm deuteration level and chemical purity. A comprehensive Certificate of Analysis (COA) detailing isotopic purity (D-atom %), chemical assay, and impurity profile is provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from strong bases and reactive metals. For long-term storage under an inert atmosphere (e.g., nitrogen or argon), please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (GC)	≥ 98.0% (chemical purity)
Isotopic Purity (D-atom %)	≥ 98.0% (by MS or NMR)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.