Description

1-[(4-Methylphenyl)Sulfonyl]-1H-Indole-3-Carbaldehyde is a high-purity sulfonated indole derivative, a crucial advanced pharmaceutical intermediate. Its value lies in its role as a versatile building block for synthesizing complex molecules with potential biological activity. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly in medicinal chemistry and process R&D.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, especially those targeting specific enzyme pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for discovering new active pharmaceutical ingredients (APIs).
• Organic Synthesis Building Block: Utilized in constructing complex heterocyclic frameworks due to its reactive aldehyde and sulfonyl-protected indole groups.
• Biochemical Research: Potential application in developing molecular probes or inhibitors for biochemical assays.
• Process Development: Employed in scaling up synthetic routes for potential APIs under Good Manufacturing Practice (GMP) conditions.

Basic Information

Product Name	1-[(4-Methylphenyl)Sulfonyl]-1H-Indole-3-Carbaldehyde
CAS No.	50562-79-3
Molecular Formula	C16H13NO3S
Molecular Weight	299.35 g/mol
Synonyms	1-Tosyl-1H-indole-3-carboxaldehyde; 1-(p-Toluenesulfonyl)-1H-indole-3-carbaldehyde; 3-Formyl-1-(4-methylphenylsulfonyl)indole; 1H-Indole-3-carboxaldehyde, 1-[(4-methylphenyl)sulfonyl]-; N-Tosylindole-3-carboxaldehyde; 1-(4-Methylbenzenesulfonyl)-1H-indole-3-carbaldehyde; 1-Tosylindole-3-carboxaldehyde; 3-Carbaldehyde-1-(p-tolylsulfonyl)indole
EINECS	Contact for details

Quality Control

Our 1-[(4-Methylphenyl)Sulfonyl]-1H-Indole-3-Carbaldehyde is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.