Description

(+)-4-Amino-α-[(tert-Butylamino)Methyl]-3,5-Dichlorobenzyl Alcohol is a chiral, substituted benzyl alcohol derivative with a specific stereochemistry and a complex amine-containing side chain. This compound matters as a sophisticated pharmaceutical intermediate or research chemical, valued for its structural complexity which makes it a key building block in synthetic organic chemistry. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and fine chemical industries for the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting adrenergic receptors.

Application

• Pharmaceutical Intermediate: A critical chiral building block in the multi-step synthesis of complex drug molecules, particularly β-adrenergic receptor agonists or antagonists.
• Research & Development: Used in medicinal chemistry programs for structure-activity relationship (SAR) studies and the discovery of new bioactive compounds.
• Chemical Synthesis: Serves as a precursor for further chemical modifications, leveraging its amino and alcohol functional groups for coupling reactions.
• Reference Standard: Employed as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	(+)-4-Amino-α-[(tert-Butylamino)Methyl]-3,5-Dichlorobenzyl Alcohol
CAS No.	50499-60-0
Molecular Formula	C13H20Cl2N2O
Molecular Weight	291.22 g/mol
Synonyms	(+)-4-Amino-α-[(tert-butylamino)methyl]-3,5-dichlorobenzyl alcohol; (R)-4-Amino-α-[(tert-butylamino)methyl]-3,5-dichlorobenzyl alcohol; 3,5-Dichloro-α-[(1,1-dimethylethyl)amino]methyl]-4-hydroxybenzenemethanamine; (R)-1-(4-Amino-3,5-dichlorophenyl)-2-(tert-butylamino)ethanol; A selective adrenergic agent intermediate; 50499-60-0; tert-Butylamino dichloro amino benzyl alcohol derivative
EINECS	Contact for details

Quality Control

Our production of (+)-4-Amino-α-[(tert-Butylamino)Methyl]-3,5-Dichlorobenzyl Alcohol adheres to strict internal quality standards to ensure batch-to-batch consistency and high chemical purity. Each lot is characterized using advanced analytical techniques including HPLC, chiral analysis, and NMR to confirm identity, purity, and enantiomeric excess. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.