Description

5-Chloro-2-Thiophenecarbonitrile is a versatile heterocyclic building block characterized by a reactive nitrile group and a chloro-substituted thiophene ring. This compound matters for its crucial role as a key synthetic intermediate in the development of advanced pharmaceuticals and agrochemicals. Industries that need it include pharmaceutical R&D, agrochemical manufacturing, and material science, where it is used to construct complex molecules for active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules containing thiophene scaffolds.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the thiophene moiety.
• Material Science: Serves as a monomer or building block for conductive polymers, organic semiconductors, and liquid crystals.
• Chemical Research: Employed in organic synthesis and medicinal chemistry for constructing complex heterocyclic compounds via further functionalization of the nitrile and chloro groups.
• Dye and Pigment Industry: Acts as an intermediate in the production of specialized dyes and organic pigments.

Basic Information

Product Name	5-Chloro-2-Thiophenecarbonitrile
CAS No.	50478-16-5
Molecular Formula	C5H2ClNS
Molecular Weight	143.59 g/mol
Synonyms	2-Cyano-5-chlorothiophene; 5-Chlorothiophene-2-carbonitrile; 5-Chloro-2-cyanothiophene; 5-Chlorothienyl-2-carbonitrile; 2-Thiophenecarbonitrile, 5-chloro-; 5-Chloro-2-thiophenenitrile
EINECS	Contact for details

Quality Control

Our 5-Chloro-2-Thiophenecarbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee compliance with your research and production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The product is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	68 - 72 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.