Description

5-Fluoropolyoxin L CAS NO 50355-67-4 is a fluorinated derivative of the polyoxin family of nucleoside antibiotics, characterized by its unique structural modification. This compound is valued for its potent and specific inhibitory activity against chitin synthase, a critical enzyme in fungal cell wall biosynthesis. It serves as a key advanced intermediate and reference standard in the research and development of novel agricultural fungicides and antifungal agents for the pharmaceutical industry.

Application

• Agricultural Fungicide Research: A critical reference standard and intermediate for developing next-generation, environmentally friendly fungicides targeting chitin synthesis in plant pathogens.
• Antifungal Agent Development: Used in pharmaceutical R&D for creating novel therapeutic agents against systemic and topical fungal infections.
• Biochemical Studies: Employed as a specific enzymatic inhibitor to study chitin synthase function and fungal cell wall biogenesis in academic and industrial laboratories.
• Mode of Action Studies: Serves as a model compound for investigating the structure-activity relationships (SAR) of nucleoside-peptide hybrid antibiotics.
• Quality Control Standard: Utilized as a high-purity analytical reference standard for the quality assurance of related agrochemical and pharmaceutical products.

Basic Information

Product Name	5-Fluoropolyoxin L
CAS No.	50355-67-4
Molecular Formula	C17H23FN6O9
Molecular Weight	474.40 g/mol
Synonyms	5-Fluoropolyoxin L; Polyoxin L, 5-fluoro-; 5-Fluoro-1-[5-O-(5-amino-5-deoxy-D-allofuranuronosyl)-β-D-ribofuranosyl]-5-fluoro-1H-pyrimidine-2,4-dione; 5-Fluoropolyoxin; 5-Fluoro-polyoxin L; 5-Fluoropolyoxin derivative; Antifungal nucleoside antibiotic derivative
EINECS	Contact for details

Quality Control

Our 5-Fluoropolyoxin L is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and specific tests for residual solvents and moisture content. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.