Description

Lithium Tri-tert-Butoxyaluminodeuteride is a specialized deuterated reducing agent, offering a controlled and selective source of deuteride. This compound is critical for applications requiring precise isotopic labeling, particularly in the synthesis of deuterated organic molecules and advanced materials. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors for deuteration reactions and mechanistic studies.

Application

• Deuterium Labeling in Pharmaceutical Intermediates: Selective reduction of carbonyls, imines, and other functional groups to introduce deuterium atoms for drug metabolism studies (ADME) and the development of deuterated active pharmaceutical ingredients (APIs).
• Synthesis of Deuterated Fine Chemicals: Production of isotopically labeled compounds for use as analytical standards, NMR solvents, and probes in spectroscopic analysis.
• Polymer and Materials Science Research: Controlled initiation or modification of polymer chains to create deuterated polymers for neutron scattering studies and structure-property investigations.
• Asymmetric Synthesis and Catalysis: Use as a stoichiometric or catalytic deuteride transfer reagent in stereoselective transformations for complex molecule synthesis.
• Mechanistic Studies in Organic Chemistry: Elucidating reaction pathways and kinetic isotope effects (KIEs) in fundamental chemical research.
• Agrochemical Development: Synthesis of deuterated analogs of pesticides and herbicides to study environmental fate and metabolic pathways.

Basic Information

Product Name	Lithium Tri-tert-Butoxyaluminodeuteride
CAS No.	50306-58-6
Molecular Formula	C12H27AlD Li O3 or LiAlD(OC(CH3)3)3
Molecular Weight	245.29 g/mol (for monoisotopic)
Synonyms	Lithium Aluminum Deuteride tert-Butoxide; Lithium Tri-tert-butoxyaluminum Deuteride; Lithium Aluminum Deuteride Tri-tert-butoxide; LiAlD(O-t-Bu)3; LTBD; Deuterated Lithium Tri-tert-butoxyaluminum Hydride; Lithium Tri(tert-butoxy)aluminodeuteride; Aluminum, deuterohydroxytris(1,1-dimethylethoxy)-, lithium salt (1:1)
EINECS	Contact for details

Quality Control

Every batch of Lithium Tri-tert-Butoxyaluminodeuteride is manufactured and tested under stringent quality protocols to ensure high isotopic purity and chemical consistency, which are paramount for research and process applications. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing assay, isotopic enrichment (D-content), and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) in a cool, dry, and well-ventilated area, away from heat and ignition sources. Due to its moisture-sensitive and easily oxidized nature, the container must be kept sealed and handled under anhydrous conditions to maintain product integrity. Recommended storage temperature: 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Assay (Titration)	≥ 95.0%
Deuterium Content	≥ 98 atom % D
Solubility	Soluble in common organic solvents (e.g., THF, toluene)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.