Description

Bromotris(Dimethylamino)Phosphonium Hexafluorophosphate is a highly reactive and versatile phosphonium salt reagent, primarily valued for its role as a powerful coupling agent and catalyst in advanced organic synthesis. Its significance lies in facilitating efficient and high-yielding reactions, particularly in the formation of complex molecular architectures under mild conditions. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries, where precision and reliability in synthetic pathways are paramount.

Application

• Peptide Coupling Reagent: A key reagent in solid-phase and solution-phase peptide synthesis for forming amide bonds, offering advantages in reduced racemization.
• Pharmaceutical Intermediate Synthesis: Used in the synthesis of active pharmaceutical ingredients (APIs) and complex heterocyclic compounds.
• Agrochemical Production: Employed in the manufacturing of advanced pesticides and herbicides requiring specific phosphonium-based intermediates.
• Polymer Chemistry: Acts as a catalyst or initiator in the synthesis of specialized polymers and functional materials.
• Ligand and Catalyst Preparation: Serves as a precursor for generating novel phosphine ligands and organometallic catalysts.
• Chemical Research & Development: A valuable tool in academic and industrial R&D for exploring new synthetic methodologies and reaction mechanisms.

Basic Information

Product Name	Bromotris(Dimethylamino)Phosphonium Hexafluorophosphate
CAS No.	50296-37-2
Molecular Formula	C6H18BrN3P•PF6
Molecular Weight	403.07 g/mol
Synonyms	Bromotris(dimethylamino)phosphonium Hexafluorophosphate; Tris(dimethylamino)bromophosphonium Hexafluorophosphate; (Dimethylamino)tribromophosphonium Hexafluorophosphate; BroP Reagent; Bromo-tris-(dimethylamino)-phosphonium Hexafluorophosphate; Phosphonium, bromotris(dimethylamino)-, hexafluorophosphate(1-); BroP(PF6); CAS 50296-37-2
EINECS	Contact for details

Quality Control

Our Bromotris(Dimethylamino)Phosphonium Hexafluorophosphate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and production. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., argon or nitrogen) when not in use to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.